(1)Raw materials

Iyo mbishi yeHPMC hollow capsule inonyanya kutorwa kubva kune yakachena yakasikwa chirimwa fiber (pine muti), inoshamwaridzana nenharaunda, yakachengeteka uye yakavimbika.

Gelatin hollow capsule inonyanya kutorwa kubva kune collagen mumatehwe emhuka nemapfupa.Mukudhirowa kwekuita, huwandu hwakawanda hwezvikamu zvemakemikari zvinowedzerwa, izvo zviri nyore kuunza hutachiona hwechirwere chemombe uye chirwere chetsoka nemuromo, nezvimwewo,.Mumakore achangopfuura, chiitiko che "Poison Capsule" chakafumura matambudziko mazhinji echinyakare gelatin capsules, senge "blue leather glue" yakafumurwa nevezvenhau, zvichiita kuti chromium mu capsule ipfuure mwero.

(2) Kushanda & Kugadzikana Kwemakemikari

HPMC is a cellulose derivative neinertness yakasimba, kushambidzika kwakafara, kugadzikana kwemakemikari zvimiro, hapana muchinjika-wekuita nealdehyde-ine zvinodhaka, uye hapana kunonoka kuparara.

Lysine inoramba iri mugelatin, Paunenge uchishandisa gelatin mu capsule, pachava nekuparara kwekunonoka chiitiko.Iyo yakanyanya kuderedza zvinodhaka zvemukati zvichave neMallard reaction negelatin (Browning Reaction).Kana mushonga une aldehyde, reductive sugar-based chemicals, kana vitamin C, saka hazvina kukodzera kushandiswa mugelatin hollow capsule.

(3) Mvura yemvura

Mvura yemvura yegelatin hollow capsule inenge 12.5% ​​kusvika 17.5%.Iyo gelatin capsule ine yakakwira yemvura yemukati inoita kutora hunyoro hwemukati wemushonga kana kunyudzwa mvura nekuzadza kwayo, ichiita iyo capsule yakapfava kana brittle, inokanganisa iyo yakazara mushonga pachayo.

Mvura yemukati yeHPMC hollow capsule ingangoita 3% kusvika 9%, iyo isingaite pamwe nekuzadza zviri mukati, uye inogona kuchengetedza yakanaka yemuviri zvimiro sekuoma kana uchizadza zvinodhaka zviri mukati mezvivakwa zvakasiyana, Kunyanya yakakodzera hygroscopicity uye kuzadza hunyoro. mishonga inonzwisisika.

(4) Kuchengetedza kusara

Chinhu chikuru chegelatin hollow capsule ipuroteni, iyo iri nyore kubereka mabhakitiriya uye tupukanana.Preservatives uye bacteriostatic agents, inogona kusara mu capsule kudzivirira kukura kwe microbial panguva yekugadzirwa.Kana iyo mari ikadarika imwe nhanho, iyo arsenic yemukati inogona kupedzisira yapfuudzwa.Panguva imwecheteyo, iyo gelatin hollow capsules inoda kuvharirwa ne ethylene oxide mushure mekugadzirwa kwapera, uye paizova ne chlorohydrin mushure me ethylene oxide sterilization.Nepo Chlorohydrin zvisaririra zvinorambidzwa kushandiswa.

HPMC hollow capsules haidi kuwedzera chero zvigadziriso mukugadzira, haidi kuvharirwa, inogona kuzadzisa zviyero zvenyika, uye ane hutano egirinhi makapule asina chero asara uye anochengetedza.

(5) Kuchengeta

HPMC hollow capsules ine yakasununguka yekuchengetedza mamiriro, patembiricha ye10 kusvika 30 ° C, uye hunyoro huri pakati pe35% ne65%, iyo isingapfave kana kuomesa uye kuita brittle.Iyo HPMC hollow capsule ine friability ye ≤ 2% pane humidity ye35% uye capsule shanduko ye ≤ 1% pane tembiricha ye80 ° C;Kuchengeta uye kutakura munzvimbo dzese dzemamiriro ekunze harisi dambudziko.

Gelatin capsules inotarisana nekunamatira pasi pemvura yakakwirira;kuoma kana friability pasi pemvura yakadzika, uye inotsamira kwakasimba pane tembiricha uye hunyoro hwenzvimbo yekuchengetedza.

(6) The zvakatipoteredza ushamwari

Kubviswa kweHPMC hollow capsule raw materials kunoitwa nekubviswa kwemuviri.Inobviswa pamuti wepaini uye haiburitse kunhuwa kwakaora.Inoderedzawo zvakanyanya huwandu hwemvura inoshandiswa uye inoderedza kusvibiswa kwezvakatipoteredza.Hapana zvinhu zvinokuvadza zvinowedzerwa panguva yekuita uye hapana kusvibiswa kwezvakatipoteredza.

Gelatin hollow capsules inogadzirwa neganda remhuka uye pfupa seyakagadzirwa, iyo inobatwa nemakemikari uye yakaviriswa.Iyo nzira inowedzera huwandu hukuru hwezvikamu zvemakemikari, inogadzira kunhuhwirira kukuru panguva yekugadzira, uye inoshandisa huwandu hukuru hwemvura.Kubudisa kusvibiswa kwakakomba;Zvakare gelatin tsvina yekudzokorodza yakaderera, uye huwandu hukuru hwekusvibisa masosi hunogadzirwa panguva yekurasa marara ayo.

(7) Kuzviparadzanisa nevamwe nemhepo yekunze

Iyo mbishi zvinhu zveHPMC hollow capsules inoona kuti inogona kunyatso paradzanisa zviri mukati kubva kunze kwenyika uye kudzivirira zvinokanganisa nemhepo, uye hupenyu hwayo hwesherufu kazhinji mwedzi makumi maviri nemana.

Iyo gelatin capsule ine nguva inoshanda yeinenge 18 mwedzi, nepo kune zvakare kuchengetedza nguva isati yashandiswa inoita kuti capsule ive nehupfupi hupenyu hwesherufu, iyo inokanganisa zvakananga hupenyu hwesherufu yemushonga.

(8) Kudzivisa kukura kwebhakitiriya

Iyo huru yemidziyo yeHPMC hollow capsules ndeye plant fiber, iyo isingango wedzera mabhakitiriya, asiwo inodzivirira kukura kwebhakitiriya.Ongororo dzakaratidza kuti HPMC hollow capsules inogona kuchengetwa munzvimbo yakajairika kwenguva yakareba, uye huwandu hwehutachiona hunogona kuchengetwa pasi peyakajairwa renji.

Iyo huru mbishi yegelatin hollow capsule ndeye collagen, uye collagen ibhakitiriya tsika yepakati, iyo inobatsira mabhakitiriya kuwanda.Kana kurapwa kusina kunaka, nhamba yebhakitiriya ichapfuura chiyero uye ichawedzera.

End.